Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990296 | 0.84 | PNMT (0.46) | OPRM1OPRD1OPRK1OPRL1SLC6A2 | |
| SCHEMBL8990470 | 0.80 | IDO1 (0.46) | SLC6A2SLC6A4IDO1 | |
| SCHEMBL22816111 | 0.73 | HTR2C (0.57) | TACR1CHRM2 | |
| SCHEMBL8990301 | 0.73 | SLC6A2 (0.54) | SLC6A2SLC6A4 | |
| SCHEMBL11834096 | 0.73 | IDO1 (0.44) | OPRM1OPRD1OPRK1OPRL1SLC6A2 | |
| SCHEMBL4387326 | 0.73 | IDO1 (0.57) | OPRM1OPRD1OPRK1OPRL1IDO1 | |
| SCHEMBL1498492 | 0.70 | LRRK2 (0.36) | TACR1PNMT | |
| SCHEMBL8990348 | 0.70 | CARM1 (0.53) | IDO1TACR1 | |
| SCHEMBL1498766 | 0.68 | TSHR (0.45) | — | |
| SCHEMBL15322118 | 0.68 | OPRL1 (0.52) | OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |