SCHEMBL899051

SCHEMBL899051

CN(C)C(=S)SSSSCCC[Si](C)(C)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
MGLL Q99685 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
FAAH O00519 1/20 0.39
JAK2 O60674 1/20 0.39
BBOX1 O75936 1/20 0.39
TP53 P04637 1/20 0.39
ALDH2 P05091 1/20 0.39
HSP90AA1 P07900 1/20 0.39
CYP3A4 P08684 1/20 0.39
FBP1 P09467 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
LOX P28300 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2022197 0.95 KDM4E (0.35) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL1259017 0.83 KDM4E (0.35) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL444368 0.81 ALDH1A1 (0.36) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL899076 0.80
SCHEMBL444848 0.78 KDM4E (0.34) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL13505192 0.75 ALDH1A1 (0.40) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL11820328 0.73 ALDH1A1 (0.57) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL442401 0.73 ALDH1A1 (0.39) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL446923 0.71 ALDH1A1 (0.36) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL4920363 0.71 ALDH1A1 (0.36) ALDH1A1LMNAHTTMGLLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10344147-B2 Functionalized polymer blend for a tire TRINSEO EUROPE GMBH (CH) 2019-07-09 US disclosed
EP-3480031-A1 POLYMER BLEND Trinseo Europe GmbH (CH) 2019-05-08 EP disclosed
EP-2895494-B1 SILANE SULFIDE MODIFIED ELASTOMERIC POLYMERS TRINSEO EUROPE GMBH (CH) 2018-07-18 EP disclosed
US-20180037059-A1 A Polymer Blend for a Tire TRINSEO EUROPE GMBH (CH) 2018-02-08 US disclosed
US-20180016424-A1 Functionalized Polymer Blend for a Tire TRINSEO EUROPE GMBH (CH) 2018-01-18 US disclosed
EP-3059099-B1 A polymer blend for a tire TRINSEO EUROPE GMBH (CH) 2018-01-17 EP disclosed
EP-3059256-B1 A functionalized polymer blend for a tire TRINSEO EUROPE GMBH (CH) 2017-11-15 EP disclosed
EP-2895515-B1 AMINO SILANE-MODIFIED POLYMERS TRINSEO EUROPE GMBH (CH) 2017-08-16 EP disclosed
US-9683066-B2 Modified polymer compositions TRINSEO EUROPE GMBH (CH) 2017-06-20 US disclosed
US-9586980-B2 Silane sulfide modified elastomeric polymers TRINSEO EUROPE GMBH (CH) 2017-03-07 US disclosed
EP-2516474-B9 MODIFIED POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2015-04-08 EP disclosed
US-20150086735-A1 Modified Polymer Compositions TRINSEO EUROPE GMBH (CH) 2015-03-26 US disclosed
US-8921502-B2 Modified polymer compositions STYRON EUROPE GMBH (CH) 2014-12-30 US disclosed
US-8895684-B2 Modified polymer compositions STYRON EUROPE GMBH (CH) 2014-11-25 US disclosed
WO-2014040639-A1 SILANE SULFIDE MODIFIED ELASTOMERIC POLYMERS STYRON EUROPE GMBH (CH) 2014-03-20 WO disclosed
WO-2014040640-A1 AMINO SILANE-MODIFIED POLYMERS STYRON EUROPE GMBH (CH) 2014-03-20 WO disclosed
EP-2516474-B1 MODIFIED POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2013-11-06 EP disclosed
US-20130202830-A1 MODIFIED POLYMER COMPOSITIONS TRINSEO EUROPE GMBH (CH) 2013-08-08 US disclosed
US-20120316289-A1 MODIFIED POLYMER COMPOSITIONS DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT 2012-12-13 US disclosed
WO-2012041804-A2 POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2012-04-05 WO disclosed