Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444368 | 0.86 | ALDH1A1 (0.36) | KDM4EMEN1FAAHJAK2BBOX1 | |
| SCHEMBL899051 | 0.83 | ALDH1A1 (0.39) | KDM4EMEN1FAAHJAK2BBOX1 | |
| SCHEMBL5610926 | 0.82 | — | — | |
| SCHEMBL209609 | 0.80 | — | — | |
| SCHEMBL442401 | 0.80 | ALDH1A1 (0.39) | KDM4EMEN1FAAHJAK2BBOX1 | |
| SCHEMBL2022197 | 0.79 | KDM4E (0.35) | KDM4EMEN1FAAHJAK2BBOX1 | |
| SCHEMBL444848 | 0.78 | KDM4E (0.34) | KDM4EMEN1FAAHJAK2BBOX1 | |
| SCHEMBL15239905 | 0.76 | — | — | |
| SCHEMBL10829158 | 0.74 | ALDH1A1 (0.40) | KDM4EMEN1FAAHJAK2BBOX1 | |
| SCHEMBL2565956 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993659-B2 | Rubber composition and pneumatic tire | THE YOKOHAMA RUBBER COMPANY, LIMITED (JP) | 2015-03-31 | — | — | US | claimed |
| US-20140155524-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | THE YOKOHAMA RUBBER COMPANY, LIMITED (JP) | 2014-06-05 | — | — | US | claimed |
| US-6753374-B1 | MIXTURE WITH SILICA FILLER AND THIURAM DISULFIDE ACCELERATOR; TIRE TREADS; FREE OF DIPHENYLGUANIDINE | UNIROYAL CHEMICAL COMPANY, INC. | 2004-06-22 | — | — | US | claimed |
| EP-1290080-A1 | RUBBER COMPOSITIONS AND METHOD FOR INCREASING THE MOONEY SCORCH VALUE | Uniroyal Chemical Company, Inc. (US) | 2003-03-12 | — | — | EP | claimed |
| US-6525110-B1 | Silica containing vulcanizing rubber for tire treads; improved processability; low heat generation, abrasion resistance | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2003-02-25 | — | — | US | claimed |
| WO-2001094461-A1 | RUBBER COMPOSITIONS AND METHOD FOR INCREASING THE MOONEY SCORCH VALUE | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2001-12-13 | — | — | WO | claimed |
| US-6191247-B1 | POLYSILSESQUIOXANE-POLYSILOXANE ADDUCT OR COPOLYMER MIXED WITH A SULFUR COMPOUND | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2001-02-20 | — | — | US | claimed |
| US-6177505-B1 | IMPROVES THE PROCESSABILITY OF THE UNVULCANIZED RUBBER COMPOSITION, WITHOUT SUBSTANTIALLY IMPAIRING THE PROPERTIES OF THE SILICA-CONTAINING VULCANIZING RUBBER COMPOSITION | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2001-01-23 | — | — | US | claimed |
| US-6033597-A | COMPOUNDING AGENT COMPRISING A MIXTURE OF A POLYSILOXANE HAVING AN ALKOXYSILYL GROUP; AND A SULFUR CONTAINING SILANE COUPLER. | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2000-03-07 | — | — | US | claimed |
| EP-0708137-B1 | Vulcanizable rubber composition and tire prepared therefrom | UNIROYAL ENGLEBERT GMBH (DE) | 1999-03-31 | — | — | EP | claimed |
| EP-0708136-B1 | Rubber blend and tread base prepared therefrom | UNIROYAL ENGLEBERT GMBH (DE) | 1999-03-03 | — | — | EP | claimed |
| US-12630696-B2 | Rubber composition, and tire | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2026-05-19 | — | — | US | disclosed |
| EP-4349616-B1 | RUBBER COMPOSITION FOR TIRE, TREAD RUBBER, AND TIRE | BRIDGESTONE CORP (JP) | 2026-05-06 | — | — | EP | disclosed |
| EP-4737489-A1 | CATALYST COMPOSITION PREPARATION METHOD AND CONJUGATED DIENE-BASED POLYMER PREPARATION METHOD | LG CHEM, LTD. (KR) | 2026-05-06 | — | — | EP | disclosed |
| US-12617879-B2 | Neodymium-catalyzed conjugated diene-based polymer and rubber composition comprising same | LG CHEM, LTD. (KR) | 2026-05-05 | — | — | US | disclosed |
| EP-0767179-B1 | Method for producing a rubber composition | BRIDGESTONE CORP (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0763564-B1 | Elastomeric composition useful for tyre treads | ENICHEM SPA (IT) | 2001-03-21 | — | — | EP | disclosed |
| US-6191247-B1 | POLYSILSESQUIOXANE-POLYSILOXANE ADDUCT OR COPOLYMER MIXED WITH A SULFUR COMPOUND | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| US-6117927-A | MODIFYING TERMINAL OF A DIENE RUBBER WITH A SILANE MODIFIER HAVING A SPECIFIC FUNCTIONALITY, | BRIDGESTONE CORPORATION (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0763564-A2 | elastomeric composition useful for tyre treads | ENICHEM ELASTOMERI S.r.l. (IT) | 1997-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617879-B2 | Neodymium-catalyzed conjugated diene-based polymer and rubber composition comprising same | RPA1, RAD1, COL1A1 | KDM4E 2760/4885MEN1 634/4885FAAH 4452/4885 |
| US-12630696-B2 | Rubber composition, and tire | THRB, RIF1, THRA | KDM4E 1842/4885MEN1 988/4885FAAH 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.