SCHEMBL446923

SCHEMBL446923

CCO[Si](CCSSSSC(=S)N(C)C)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
FAAH O00519 1/20 0.36
JAK2 O60674 1/20 0.36
BBOX1 O75936 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
ALDH2 P05091 1/20 0.36
HSP90AA1 P07900 1/20 0.36
CYP3A4 P08684 1/20 0.36
FBP1 P09467 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
LOX P28300 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL444848 0.91 KDM4E (0.34) ALDH1A1KDM4EMEN1FAAHJAK2
SCHEMBL442401 0.84 ALDH1A1 (0.39) ALDH1A1KDM4EMEN1FAAHJAK2
SCHEMBL329679 0.79
SCHEMBL380457 0.75
SCHEMBL444368 0.75 ALDH1A1 (0.36) ALDH1A1KDM4EMEN1FAAHJAK2
SCHEMBL2950408 0.73
SCHEMBL31541489 0.72
SCHEMBL11820328 0.71 ALDH1A1 (0.57) ALDH1A1KDM4EMEN1FAAHJAK2
SCHEMBL899051 0.71 ALDH1A1 (0.39) ALDH1A1KDM4EMEN1FAAHJAK2
SCHEMBL356442 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 872 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11852647-B2 Method for predicting the rubber reinforcing effect of organic-inorganic composite for rubber reinforcement LG CHEM, LTD. 2023-12-26 US claimed
EP-3534144-B1 METHOD FOR PREDICTING RUBBER REINFORCEMENT EFFECT OF ORGANIC-INORGANIC COMPOSITE FOR RUBBER REINFORCEMENT LG CHEMICAL LTD (KR) 2021-12-22 EP claimed
US-11059956-B2 Organic-inorganic composite for rubber reinforcement, method for preparing the same, and rubber composition for tires comprising the same LG CHEM, LTD. (KR) 2021-07-13 US claimed
EP-3533825-B1 ORGANIC-INORGANIC COMPOSITE FOR REINFORCING RUBBER, PREPARATION METHOD THEREFOR, AND TIRE RUBBER COMPOSITION COMPRISING SAME LG CHEMICAL LTD (KR) 2020-10-21 EP claimed
US-20200131341-A1 Organic-Inorganic Composite for Rubber Reinforcement, Method for Preparing the Same, and Rubber Composition for Tires Comprising the Same LG CHEM, LTD. (KR) 2020-04-30 US claimed
US-20190310176-A1 Method for Predicting the Rubber Reinforcing Effect of Organic-Inorganic Composite for Rubber Reinforcement LG CHEM, LTD. (KR) 2019-10-10 US claimed
EP-3534144-A2 METHOD FOR PREDICTING RUBBER REINFORCEMENT EFFECT OF ORGANIC-INORGANIC COMPOSITE FOR RUBBER REINFORCEMENT LG Chem, Ltd. (KR) 2019-09-04 EP claimed
EP-3533825-A1 ORGANIC-INORGANIC COMPOSITE FOR REINFORCING RUBBER, PREPARATION METHOD THEREFOR, AND TIRE RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2019-09-04 EP claimed
US-7338999-B2 Rubber composition for tire tread and pneumatic tire using the same SUMITOMO RUBBER INDUSTRIES, INC. (JP) 2008-03-04 US claimed
EP-4737514-A1 RUBBER COMPOSITION AND TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-05-06 EP disclosed
EP-4737489-A1 CATALYST COMPOSITION PREPARATION METHOD AND CONJUGATED DIENE-BASED POLYMER PREPARATION METHOD LG CHEM, LTD. (KR) 2026-05-06 EP disclosed
EP-4349616-B1 RUBBER COMPOSITION FOR TIRE, TREAD RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2026-05-06 EP disclosed
US-12617879-B2 Neodymium-catalyzed conjugated diene-based polymer and rubber composition comprising same LG CHEM, LTD. (KR) 2026-05-05 US disclosed
US-12606651-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-21 US disclosed
US-20020026003-A1 Rubber composition for type tread SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2002-02-28 US disclosed
EP-1172406-A2 Rubber composition for tyre tread SUMITOMO RUBBER INDUSTRIES LTD. (JP) 2002-01-16 EP disclosed
EP-0767179-B1 Method for producing a rubber composition BRIDGESTONE CORP (JP) 2001-06-27 EP disclosed
US-6117927-A MODIFYING TERMINAL OF A DIENE RUBBER WITH A SILANE MODIFIER HAVING A SPECIFIC FUNCTIONALITY, BRIDGESTONE CORPORATION (JP) 2000-09-12 US disclosed
EP-0885925-A1 Tire, rubber composition, and vulcanized rubber BRIDGESTONE CORPORATION (JP) 1998-12-23 EP disclosed
EP-0767179-A2 Method for producing a rubber composition Bridgestone Corporation (JP) 1997-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617879-B2 Neodymium-catalyzed conjugated diene-based polymer and rubber composition comprising same RPA1, RAD1, COL1A1 ALDH1A1 2894/4885KDM4E 2760/4885MEN1 634/4885
US-12606651-B2 Rubber composition and tire ATR, RAD51, SELE ALDH1A1 3020/4885KDM4E 2322/4885MEN1 3677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.