Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990739 | 0.91 | MAOB (0.47) | MAOBTAAR1FDFT1 | |
| SCHEMBL9664336 | 0.89 | ALOX5 (0.41) | MAOBTAAR1 | |
| SCHEMBL8990636 | 0.85 | MAOB (0.47) | MAOBTAAR1 | |
| SCHEMBL9664848 | 0.85 | TAAR1 (0.40) | MAOBTAAR1 | |
| SCHEMBL8990753 | 0.84 | MAOB (0.61) | MAOBTAAR1DAOCTSSCTSK | |
| SCHEMBL8990645 | 0.84 | APP (0.49) | MAOBTAAR1CTSSCTSKKIF11 | |
| SCHEMBL9664166 | 0.84 | RARB (0.46) | — | |
| SCHEMBL8990775 | 0.83 | DAO (0.41) | DAOKIF11 | |
| SCHEMBL9664954 | 0.83 | RARB (0.47) | MAOBTAAR1KIF11 | |
| SCHEMBL9809579 | 0.83 | MAOB (0.63) | MAOBTAAR1DAOCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| WO-1990008757-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |