Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | DRD4 | P21917 | 6/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990838 | 0.94 | GHSR (0.51) | GHSRAGTR1DRD2DRD4DRD3 | |
| SCHEMBL8990824 | 0.94 | GHSR (0.49) | GHSRAGTR1DRD2DRD4DRD3 | |
| SCHEMBL8991111 | 0.91 | GHSR (0.57) | GHSRAGTR1MCHR1TACR1 | |
| SCHEMBL8991024 | 0.90 | GHSR (0.51) | GHSRAGTR1DRD2DRD4DRD3 | |
| SCHEMBL8990798 | 0.89 | GHSR (0.44) | GHSRDRD2DRD4DRD3HTR7 | |
| SCHEMBL8990932 | 0.89 | GHSR (0.43) | GHSRDRD2DRD4DRD3MCHR1 | |
| SCHEMBL8991117 | 0.88 | AGTR1 (0.41) | GHSRAGTR1MEN1KMT2ASCN9A | |
| SCHEMBL8991114 | 0.88 | AGTR1 (0.41) | GHSRAGTR1MEN1KMT2ASCN9A | |
| SCHEMBL8990827 | 0.86 | GHSR (0.59) | GHSRDRD2DRD4DRD3MCHR1 | |
| SCHEMBL8990704 | 0.86 | GHSR (0.58) | GHSRDRD2DRD4DRD3MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |