Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991117 | 1.00 | AGTR1 (0.41) | AGTR1GHSRTAS1R3TAS1R1AGTR2 | |
| SCHEMBL8990818 | 0.90 | GHSR (0.47) | AGTR1GHSRTACR1 | |
| SCHEMBL8990812 | 0.90 | GHSR (0.47) | AGTR1GHSRTACR1 | |
| SCHEMBL8991023 | 0.90 | GHSR (0.42) | AGTR1GHSRTACR1 | |
| SCHEMBL8991029 | 0.90 | GHSR (0.42) | AGTR1GHSRTACR1 | |
| SCHEMBL8990799 | 0.88 | GHSR (0.50) | AGTR1GHSRMEN1KMT2ASCN9A | |
| SCHEMBL8990824 | 0.85 | GHSR (0.49) | AGTR1GHSRMEN1KMT2ASCN9A | |
| SCHEMBL8991074 | 0.84 | AGTR1 (0.35) | AGTR1TAS1R3TAS1R1AGTR2PPARG | |
| SCHEMBL8990838 | 0.84 | GHSR (0.51) | AGTR1GHSRMEN1KMT2ASCN9A | |
| SCHEMBL8991073 | 0.83 | AGTR1 (0.46) | AGTR1GHSRMEN1KMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |