Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.37 |
| ▸ | SMO | Q99835 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991095 | 0.89 | TACR1 (0.41) | TACR1ACACBAGTR1GHSR | |
| SCHEMBL8990768 | 0.85 | GHSR (0.43) | TACR1OPRM1OPRD1AGTR1GHSR | |
| SCHEMBL8990851 | 0.80 | TACR1 (0.38) | TACR1OPRM1OPRD1AGTR1GHSR | |
| SCHEMBL8990911 | 0.78 | SMN1; SMN2 (0.35) | TACR1OPRM1OPRD1AGTR1GHSR | |
| SCHEMBL8991030 | 0.78 | GHSR (0.38) | TACR1OPRM1OPRD1AGTR1GHSR | |
| SCHEMBL8990738 | 0.77 | AGTR1 (0.36) | TACR1OPRM1AGTR1GHSR | |
| SCHEMBL8990862 | 0.77 | GHSR (0.45) | TACR1OPRM1AGTR1GHSR | |
| SCHEMBL8991037 | 0.77 | GHSR (0.44) | TACR1OPRM1OPRD1AGTR1GHSR | |
| SCHEMBL8991035 | 0.77 | MME (0.36) | TACR1OPRM1OPRD1AGTR1GHSR | |
| SCHEMBL8990771 | 0.76 | GHSR (0.42) | TACR1OPRM1OPRD1AGTR1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |