Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145807 | 0.93 | LMNA (0.64) | L3MBTL1LMNAMAOBTAAR1GCGR | |
| SCHEMBL12603779 | 0.93 | L3MBTL1 (0.64) | L3MBTL1LMNAMAOBTAAR1PTGS1 | |
| SCHEMBL8990730 | 0.86 | MAOB (0.57) | L3MBTL1LMNAMAOBTAAR1PTGS1 | |
| SCHEMBL8990619 | 0.86 | MAOB (0.57) | L3MBTL1LMNAMAOBTAAR1PTGS1 | |
| SCHEMBL8990679 | 0.85 | CYP17A1 (0.56) | L3MBTL1LMNAMAOBTAAR1PTGS1 | |
| SCHEMBL13925528 | 0.85 | — | — | |
| SCHEMBL131869 | 0.85 | — | — | |
| SCHEMBL21422626 | 0.84 | L3MBTL1 (0.60) | L3MBTL1LMNAMAOBTAAR1PTGS1 | |
| SCHEMBL7552100 | 0.84 | MAOB (0.59) | L3MBTL1LMNAMAOBTAAR1PTGS1 | |
| Ammonia Solution, Strong SCHEMBL143304 | 0.83 | LMNA (0.70) | L3MBTL1LMNATAAR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0429558-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE. | MERCK PATENT GMBH (DE) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990008757-A1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |