Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990798 | 0.91 | GHSR (0.44) | XIAPMEN1KMT2AKCNA5KCNH2 | |
| SCHEMBL8990741 | 0.91 | GHSR (0.45) | XIAPMEN1KMT2AKCNA5KCNH2 | |
| SCHEMBL8991087 | 0.91 | TACR1 (0.39) | TACR1GHSRAGTR1 | |
| SCHEMBL8991077 | 0.89 | FPR1 (0.36) | XIAPKMT2AROCK1GHSRAGTR1 | |
| SCHEMBL8991098 | 0.88 | AGTR1 (0.36) | XIAPMEN1KMT2AROCK1GHSR | |
| SCHEMBL8991112 | 0.86 | GHSR (0.37) | MEN1KMT2AKCNA5KCNH2TACR1 | |
| SCHEMBL8990712 | 0.86 | GHSR (0.43) | MTNR1AMTNR1BXIAPMEN1KMT2A | |
| SCHEMBL8990834 | 0.85 | GHSR (0.44) | MEN1KMT2AKCNA5KCNH2TACR1 | |
| SCHEMBL8990932 | 0.85 | GHSR (0.43) | MEN1KMT2AKCNA5KCNH2TACR1 | |
| SCHEMBL8990946 | 0.85 | GHSR (0.40) | XIAPKCNA5TACR1GHSRAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |