Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK5 | O95279 | 1/20 | 0.31 |
| ▸ | KCNK17 | Q96T54 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991083 | 0.94 | GHSR (0.43) | GHSRKCNA5KCNH2ADRB2ADRB1 | |
| SCHEMBL8990948 | 0.92 | GHSR (0.47) | GHSRAGTR1 | |
| SCHEMBL8990904 | 0.91 | GHSR (0.42) | GHSR | |
| SCHEMBL8990877 | 0.91 | GHSR (0.42) | GHSRKCNA5KCNH2DRD2DRD4 | |
| SCHEMBL8990719 | 0.90 | SMN1; SMN2 (0.34) | GHSRAGTR1 | |
| SCHEMBL8990767 | 0.90 | GHSR (0.48) | GHSRKCNA5KCNH2ALOX5EPHX2 | |
| SCHEMBL8990881 | 0.89 | GHSR (0.44) | GHSRKCNA5KCNH2DRD2DRD4 | |
| SCHEMBL8990957 | 0.89 | GHSR (0.43) | GHSRKCNA5KCNH2HSD11B1DRD2 | |
| SCHEMBL8990853 | 0.88 | GHSR (0.37) | GHSRKCNA5KCNH2ADRB2ADRB1 | |
| SCHEMBL8991016 | 0.87 | GHSR (0.44) | GHSRKCNA5KCNH2ALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |