Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990881 | 0.95 | GHSR (0.44) | GHSRDRD2DRD4DRD3KCNA5 | |
| SCHEMBL8991083 | 0.94 | GHSR (0.43) | GHSRDRD2DRD4DRD3KCNA5 | |
| SCHEMBL8990853 | 0.93 | GHSR (0.37) | GHSRKCNA5KCNH2OPRM1OPRK1 | |
| SCHEMBL8990751 | 0.93 | GHSR (0.47) | GHSROPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8991009 | 0.92 | GHSR (0.42) | GHSRDRD2DRD4DRD3KCNA5 | |
| SCHEMBL8991001 | 0.92 | GHSR (0.42) | GHSR | |
| SCHEMBL8990873 | 0.89 | GHSR (0.43) | GHSRDRD2DRD4DRD3KCNA5 | |
| SCHEMBL8991037 | 0.88 | GHSR (0.44) | GHSRDRD2DRD4DRD3KCNA5 | |
| SCHEMBL8990759 | 0.87 | GHSR (0.48) | GHSRDRD2DRD4DRD3 | |
| SCHEMBL8990795 | 0.87 | GHSR (0.43) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |