Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | PRF1 | P14222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991083 | 0.93 | GHSR (0.43) | GHSRADRB2ADRB1ADRB3KCNA5 | |
| SCHEMBL8990881 | 0.93 | GHSR (0.44) | GHSRKCNA5KCNH2 | |
| SCHEMBL8990957 | 0.93 | GHSR (0.43) | GHSRKCNA5KCNH2OPRM1OPRK1 | |
| SCHEMBL8990997 | 0.92 | GHSR (0.40) | GHSRADRB2ADRB1ADRB3AGTR1 | |
| SCHEMBL8990891 | 0.91 | GHSR (0.36) | GHSRAGTR1 | |
| SCHEMBL8990873 | 0.88 | GHSR (0.43) | GHSRADRB2ADRB1ADRB3KCNA5 | |
| SCHEMBL8991030 | 0.87 | GHSR (0.38) | GHSRAGTR1OPRM1OPRK1OPRL1 | |
| SCHEMBL8990840 | 0.86 | GHSR (0.41) | GHSRAGTR1 | |
| SCHEMBL8990887 | 0.86 | GHSR (0.46) | GHSRKCNA5KCNH2OPRM1OPRK1 | |
| SCHEMBL8990981 | 0.86 | GHSR (0.34) | GHSRADRB2ADRB1ADRB3CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |