Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990919 | 0.91 | GHSR (0.40) | GHSRAGTR1GRM2 | |
| SCHEMBL8991104 | 0.86 | GHSR (0.38) | GHSRAGTR1ADAM17OPRM1OPRK1 | |
| SCHEMBL8990903 | 0.86 | AGTR1 (0.34) | GHSRAGTR1 | |
| SCHEMBL9694552 | 0.83 | GHSR (0.48) | GHSRAGTR1 | |
| SCHEMBL8990860 | 0.83 | GHSR (0.48) | GHSRAGTR1 | |
| SCHEMBL8990823 | 0.83 | AGTR1 (0.42) | GHSRAGTR1 | |
| SCHEMBL8990887 | 0.82 | GHSR (0.46) | GHSROPRM1OPRK1OPRL1KCNA5 | |
| SCHEMBL8990935 | 0.81 | GHSR (0.55) | GHSROPRM1OPRK1OPRL1KCNA5 | |
| SCHEMBL8990780 | 0.81 | GHSR (0.56) | GHSROPRM1OPRK1OPRL1KCNA5 | |
| SCHEMBL8990728 | 0.80 | GHSR (0.42) | GHSRAGTR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |