Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990860 | 1.00 | GHSR (0.48) | GHSRAGTR1HDAC1HDAC7MEN1 | |
| SCHEMBL8990919 | 0.92 | GHSR (0.40) | GHSRAGTR1HDAC1HDAC7MEN1 | |
| SCHEMBL8990823 | 0.90 | AGTR1 (0.42) | GHSRAGTR1 | |
| SCHEMBL8990937 | 0.88 | AGTR1 (0.38) | GHSRAGTR1 | |
| SCHEMBL8990854 | 0.86 | GHSR (0.52) | GHSRAGTR1 | |
| SCHEMBL9024772 | 0.86 | GHSR (0.52) | GHSRAGTR1HDAC1HDAC7 | |
| SCHEMBL8990884 | 0.83 | GHSR (0.36) | GHSRAGTR1 | |
| SCHEMBL8990849 | 0.81 | GHSR (0.42) | GHSRAGTR1HDAC1HDAC7MEN1 | |
| SCHEMBL8990903 | 0.81 | AGTR1 (0.34) | GHSRAGTR1 | |
| SCHEMBL8990986 | 0.80 | AGTR1 (0.47) | GHSRAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513974-A1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |