Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | PRF1 | P14222 | 1/20 | 0.30 |
| ▸ | IDH2 | P48735 | 2/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990894 | 0.93 | SMN1; SMN2 (0.34) | MEN1ALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL8990719 | 0.87 | SMN1; SMN2 (0.34) | MEN1ALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL8990981 | 0.87 | GHSR (0.34) | MEN1ALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL8991083 | 0.86 | GHSR (0.43) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8991052 | 0.85 | — | — | |
| SCHEMBL8990833 | 0.85 | GHSR (0.35) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8990826 | 0.84 | FPR1 (0.34) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8990749 | 0.84 | GHSR (0.31) | — | |
| SCHEMBL8991085 | 0.82 | ADRB2 (0.38) | ALDH1A1GAAKMT2AADRB2ADRB1 | |
| SCHEMBL8990990 | 0.81 | GHSR (0.38) | MEN1ALDH1A1GAAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |