Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991003 | 0.91 | GHSR (0.51) | GHSROPRM1HDAC1TACR1AGTR1 | |
| SCHEMBL8990865 | 0.90 | GHSR (0.44) | GHSRALDH1A1KMT2AHDAC1LMNA | |
| SCHEMBL8990828 | 0.90 | GHSR (0.44) | GHSRSMN1; SMN2KMT2AOPRM1HDAC1 | |
| SCHEMBL8991034 | 0.88 | GHSR (0.60) | GHSROPRM1OPRK1OPRL1TACR1 | |
| SCHEMBL8990883 | 0.85 | SMN1; SMN2 (0.35) | GHSRSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8990911 | 0.84 | SMN1; SMN2 (0.35) | GHSRSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8991044 | 0.83 | GHSR (0.60) | GHSROPRM1OPRK1OPRL1TACR1 | |
| SCHEMBL8990897 | 0.83 | GHSR (0.47) | GHSROPRM1HDAC1TACR1AGTR1 | |
| SCHEMBL8990958 | 0.82 | GHSR (0.61) | GHSROPRM1OPRK1OPRL1TACR1 | |
| SCHEMBL8991104 | 0.82 | GHSR (0.38) | GHSROPRM1OPRK1OPRL1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |