Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.44 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SDCBP | O00560 | 1/20 | 0.34 |
| ▸ | SDC2 | P34741 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991003 | 0.90 | GHSR (0.51) | GHSRHDAC1 | |
| SCHEMBL8990913 | 0.90 | GHSR (0.45) | GHSRFPR2KMT2ANPSR1HDAC1 | |
| SCHEMBL8990704 | 0.88 | GHSR (0.58) | GHSRXIAPKMT2AMAPTSCN9A | |
| SCHEMBL8990828 | 0.88 | GHSR (0.44) | GHSRKMT2AHDAC1MAPTKDM4E | |
| SCHEMBL8991077 | 0.85 | FPR1 (0.36) | GHSRFPR1FPR2XIAPKMT2A | |
| SCHEMBL8991080 | 0.85 | FPR2 (0.35) | GHSRFPR1FPR2XIAPKMT2A | |
| SCHEMBL8990827 | 0.83 | GHSR (0.59) | GHSRKMT2ASCN9A | |
| SCHEMBL8990895 | 0.83 | GHSR (0.37) | GHSRXIAPROCK2NAMPTSCN9A | |
| SCHEMBL8990897 | 0.82 | GHSR (0.47) | GHSRHDAC1 | |
| SCHEMBL8990824 | 0.81 | GHSR (0.49) | GHSRKMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |