Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990913 | 0.91 | GHSR (0.45) | GHSRHDAC1TACR1OPRM1AGTR1 | |
| SCHEMBL8990897 | 0.91 | GHSR (0.47) | GHSRHDAC1MMEACETACR1 | |
| SCHEMBL8990828 | 0.90 | GHSR (0.44) | GHSRHDAC1MMEACETACR1 | |
| SCHEMBL8990865 | 0.90 | GHSR (0.44) | GHSRHDAC1 | |
| SCHEMBL8990816 | 0.87 | GHSR (0.68) | GHSRMMEACETACR1HRH4 | |
| SCHEMBL8990930 | 0.85 | GHSR (0.48) | GHSRMMEACETACR1HRH4 | |
| SCHEMBL8990879 | 0.85 | GHSR (0.52) | GHSRHDAC1MMEACETACR1 | |
| SCHEMBL8990820 | 0.85 | HDAC1 (0.43) | GHSRHDAC1OPRM1OPRD1AGTR1 | |
| SCHEMBL8990811 | 0.85 | HDAC1 (0.43) | GHSRHDAC1OPRM1OPRD1AGTR1 | |
| SCHEMBL8990800 | 0.84 | HRH4 (0.43) | MMEACEHRH4OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |