Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990785 | 0.92 | GHSR (0.41) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990944 | 0.90 | GHSR (0.51) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8991082 | 0.88 | GHSR (0.41) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8991075 | 0.86 | GHSR (0.46) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8991057 | 0.86 | GHSR (0.40) | GHSRAGTR1MMP2HSD17B3KMT2A | |
| SCHEMBL8991051 | 0.84 | GHSR (0.49) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990927 | 0.82 | GHSR (0.58) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990764 | 0.82 | GHSR (0.59) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990832 | 0.82 | GHSR (0.37) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990994 | 0.81 | GHSR (0.42) | GHSRAGTR1TACR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |