Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990726 | 0.94 | GHSR (0.37) | GHSRAGTR1HDAC1PTGER1DRD2 | |
| SCHEMBL8991018 | 0.93 | GHSR (0.35) | GHSRAGTR1HDAC1PTGER1MEN1 | |
| SCHEMBL8990964 | 0.92 | GHSR (0.34) | GHSRAGTR1MEN1ALDH1A1KMT2A | |
| SCHEMBL8991050 | 0.91 | GHSR (0.34) | GHSRMEN1KMT2ADRD2DRD4 | |
| SCHEMBL8990978 | 0.91 | GHSR (0.34) | GHSR | |
| SCHEMBL8990933 | 0.90 | GHSR (0.49) | GHSRAGTR1PTGER1DRD2DRD4 | |
| SCHEMBL8990880 | 0.90 | GHSR (0.42) | GHSRAGTR1HDAC1PTGER1MEN1 | |
| SCHEMBL8990833 | 0.87 | GHSR (0.35) | GHSRAGTR1HDAC1PTGER1MEN1 | |
| SCHEMBL8990916 | 0.87 | GHSR (0.39) | GHSRAGTR1DRD2DRD4DRD3 | |
| SCHEMBL8990950 | 0.87 | ADRB2 (0.33) | GHSRAGTR1HDAC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |