Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990988 | 0.94 | GHSR (0.38) | GHSRAGTR1HDAC1PTGER1DRD2 | |
| SCHEMBL8990833 | 0.93 | GHSR (0.35) | GHSRAGTR1HDAC1PTGER1 | |
| SCHEMBL8990981 | 0.92 | GHSR (0.34) | GHSRDRD2DRD4DRD3 | |
| SCHEMBL8991081 | 0.91 | GHSR (0.33) | GHSR | |
| SCHEMBL8991053 | 0.91 | GHSR (0.33) | GHSRDRD2DRD4DRD3 | |
| SCHEMBL8990759 | 0.90 | GHSR (0.48) | GHSRAGTR1PTGER1DRD2DRD4 | |
| SCHEMBL8990880 | 0.89 | GHSR (0.42) | GHSRAGTR1HDAC1PTGER1DRD2 | |
| SCHEMBL8991018 | 0.87 | GHSR (0.35) | GHSRAGTR1HDAC1PTGER1 | |
| SCHEMBL8990830 | 0.87 | ADRB2 (0.36) | GHSRAGTR1HDAC1 | |
| SCHEMBL8990964 | 0.86 | GHSR (0.34) | GHSRAGTR1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |