Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990976 | 0.91 | ANPEP (0.40) | ANPEPLNPEPAGTR1HRH4HDAC1 | |
| SCHEMBL8990864 | 0.91 | ANPEP (0.36) | ANPEPLNPEPAGTR1HRH4SRC | |
| SCHEMBL8990687 | 0.89 | ANPEP (0.35) | ANPEPLNPEPAGTR1HRH4SRC | |
| SCHEMBL8991074 | 0.87 | AGTR1 (0.35) | XIAPAGTR1AGTR2PPARGTAS1R3 | |
| SCHEMBL8991043 | 0.83 | AGTR1 (0.34) | XIAPAGTR1AGTR2PPARGTAS1R3 | |
| SCHEMBL8991114 | 0.82 | AGTR1 (0.41) | AGTR1AGTR2PPARGTAS1R3TAS1R1 | |
| SCHEMBL8991117 | 0.82 | AGTR1 (0.41) | AGTR1AGTR2PPARGTAS1R3TAS1R1 | |
| SCHEMBL8990965 | 0.79 | CCR3 (0.34) | AGTR1AGTR2FAAHCNR1CNR2 | |
| SCHEMBL8990770 | 0.78 | HDAC1 (0.31) | AGTR1HDAC1 | |
| SCHEMBL8990867 | 0.77 | CCR3 (0.34) | AGTR1AGTR2PPARGFAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |