Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991074 | 0.95 | AGTR1 (0.35) | AGTR1AGTR2MEN1KMT2ATAS1R3 | |
| SCHEMBL8990942 | 0.91 | PRMT5 (0.38) | PRMT5 | |
| SCHEMBL8990954 | 0.91 | CCR3 (0.33) | AGTR1AGTR2PRMT5PPARG | |
| SCHEMBL8990819 | 0.90 | PRMT5 (0.32) | PRMT5 | |
| SCHEMBL8991154 | 0.88 | TAS1R3 (0.32) | AGTR1AGTR2MEN1KMT2APRMT5 | |
| SCHEMBL8990980 | 0.86 | PRMT5 (0.38) | PRMT5 | |
| SCHEMBL8990867 | 0.86 | CCR3 (0.34) | AGTR1AGTR2PPARG | |
| SCHEMBL8990688 | 0.85 | HDAC1 (0.31) | AGTR1PRMT5 | |
| SCHEMBL8991068 | 0.83 | XIAP (0.36) | AGTR1AGTR2MEN1KMT2ATAS1R3 | |
| SCHEMBL8991117 | 0.83 | AGTR1 (0.41) | AGTR1AGTR2MEN1KMT2ATAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |