Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991035 | 0.94 | MME (0.36) | MMEACEGHSRAGTR1TACR1 | |
| SCHEMBL8990916 | 0.93 | GHSR (0.39) | MMEACEGHSRAGTR1TACR1 | |
| SCHEMBL8990883 | 0.93 | SMN1; SMN2 (0.35) | MMEGHSRAGTR1TACR1OPRM1 | |
| SCHEMBL8991077 | 0.91 | FPR1 (0.36) | GHSRAGTR1 | |
| SCHEMBL8991017 | 0.89 | GHSR (0.49) | MMEACEGHSRAGTR1TACR1 | |
| SCHEMBL8990908 | 0.88 | GAA (0.35) | MMEACEGHSRAGTR1TACR1 | |
| SCHEMBL8991087 | 0.87 | TACR1 (0.39) | MMEACEGHSRAGTR1TACR1 | |
| SCHEMBL8990897 | 0.87 | GHSR (0.47) | MMEACEGHSRAGTR1TACR1 | |
| SCHEMBL8991018 | 0.86 | GHSR (0.35) | GHSRAGTR1 | |
| SCHEMBL8990911 | 0.86 | SMN1; SMN2 (0.35) | GHSRAGTR1TACR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |