Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990993 | 0.94 | ADRB2 (0.35) | GAAAGTR1GHSRTSHRPRMT5 | |
| SCHEMBL8990950 | 0.88 | ADRB2 (0.33) | GAAAGTR1GHSRTSHRRAB9A | |
| SCHEMBL8991127 | 0.88 | MME (0.36) | AGTR1GHSRTACR1MMEACE | |
| SCHEMBL8990916 | 0.86 | GHSR (0.39) | AGTR1GHSRTACR1MMEACE | |
| SCHEMBL7791538 | 0.84 | GHSR (0.50) | AGTR1GHSR | |
| SCHEMBL8991087 | 0.84 | TACR1 (0.39) | AGTR1GHSRTACR1MMEACE | |
| SCHEMBL8990882 | 0.83 | ADRB2 (0.35) | GAATSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8990892 | 0.82 | ADRB2 (0.31) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL8990940 | 0.82 | KMT2A (0.35) | ALDH1A1MAPTADRB2ADRB1ADRB3 | |
| SCHEMBL8990830 | 0.82 | ADRB2 (0.36) | GAAAGTR1GHSRTSHRPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |