Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991354 | 0.90 | EGFR (0.38) | EGFRSRCHSPA5MEN1KMT2A | |
| SCHEMBL7700288 | 0.87 | KDM4E (0.44) | EGFRSRCKDM4ETSHRMAPK1 | |
| SCHEMBL8990963 | 0.86 | MEN1 (0.48) | EGFRSRCMEN1KMT2ANPC1 | |
| SCHEMBL8991004 | 0.85 | YTHDC1 (0.31) | EGFRSRC | |
| SCHEMBL8991290 | 0.82 | RET (0.33) | MEN1KMT2ANPC1RAB9ANR2F2 | |
| SCHEMBL8991228 | 0.81 | PDE4A (0.37) | EGFRSRCHSPA5MEN1KMT2A | |
| SCHEMBL8991180 | 0.80 | LRRK2 (0.43) | EGFRSRCHSPA5MEN1KMT2A | |
| SCHEMBL8991365 | 0.79 | ADORA2A (0.41) | EGFRSRCHSPA5MEN1KMT2A | |
| SCHEMBL8991221 | 0.77 | MEN1 (0.39) | SRCMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8991134 | 0.77 | GAA (0.42) | EGFRSRCMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |