Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CALML3 | P27482 | 4/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840655 | 0.87 | MAPT (0.54) | MAPTALDH1A1HPGDTP53MAOA | |
| SCHEMBL8991274 | 0.84 | MAOA (0.51) | MAPTALDH1A1HPGDTP53MAOA | |
| SCHEMBL8991395 | 0.84 | MAPT (0.45) | MAPTALDH1A1HPGDTP53LMNA | |
| SCHEMBL27462935 | 0.80 | MAPT (0.46) | MAPTALDH1A1HPGDTP53LMNA | |
| SCHEMBL9044273 | 0.74 | KEAP1 (0.47) | MAPTALDH1A1HPGDLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL8991509 | 0.73 | KEAP1 (0.46) | MAPTALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL3505104 | 0.72 | CALML3 (0.46) | MAPTMAOAMAOBCALML3GRM2 | |
| SCHEMBL3504946 | 0.72 | CALML3 (0.46) | MAPTMAOAMAOBCALML3GRM2 | |
| SCHEMBL8115548 | 0.72 | MAOA (0.55) | MAOAMAOBLMNACALML3 | |
| SCHEMBL3504948 | 0.72 | CALML3 (0.46) | MAPTMAOAMAOBCALML3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5529998-A | ANTIBACTERIAL MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0697412-A1 | Benzoxazolyl- and benzo-thiazolyl-oxazolidinones | BAYER AG (DE) | 1996-02-21 | — | — | EP | disclosed |