Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8991509 | 0.99 | KEAP1 (0.46) | KEAP1F10PKMMEN1RAB9A | |
| SCHEMBL8991274 | 0.89 | MAOA (0.51) | KEAP1PKMRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8991488 | 0.84 | PKM (0.41) | KEAP1PKMMEN1RAB9AKMT2A | |
| SCHEMBL8115548 | 0.84 | MAOA (0.55) | F10LMNA | |
| SCHEMBL8115545 | 0.79 | KEAP1 (0.43) | KEAP1PKMMEN1RAB9AKMT2A | |
| SCHEMBL9043250 | 0.75 | GRM2 (0.39) | F10MEN1KMT2ANPSR1MAPT | |
| Hydrochloric Acid SCHEMBL8991424 | 0.75 | GRM2 (0.39) | F10MEN1KMT2ANPSR1MAPT | |
| SCHEMBL8991279 | 0.74 | MAPT (0.50) | MEN1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL79733 | 0.73 | F10 (0.50) | F10 | |
| Hydrochloric Acid SCHEMBL8124261 | 0.73 | F10 (0.49) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697412-A1 | Benzoxazolyl- and benzo-thiazolyl-oxazolidinones | BAYER AG (DE) | 1996-02-21 | — | — | EP | disclosed |