Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 2/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991365 | 0.90 | ADORA2A (0.41) | ADORA2AEGFRSRCPDE4APDE4B | |
| SCHEMBL8991388 | 0.86 | PDE4A (0.50) | ADORA2AEGFRSRCPDE4APDE4B | |
| SCHEMBL8991270 | 0.85 | IGF1R (0.43) | ADORA2AEGFRSRCIGF1R | |
| SCHEMBL8990926 | 0.85 | EGFR (0.32) | EGFRSRCADK | |
| SCHEMBL8991249 | 0.82 | ADK (0.33) | EGFRSRCADK | |
| SCHEMBL8991346 | 0.82 | PDE4A (0.40) | ADORA2AEGFRSRCPDE4APDE4B | |
| SCHEMBL8991378 | 0.81 | ADORA2A (0.41) | ADORA2AEGFRSRCPDE4APDE4B | |
| SCHEMBL8991354 | 0.79 | EGFR (0.38) | ADORA2AEGFRSRCPDE4APDE4B | |
| SCHEMBL8991225 | 0.77 | PDE4A (0.42) | ADORA2AEGFRSRCPDE4APDE4B | |
| SCHEMBL8991063 | 0.76 | GAA (0.41) | EGFRSRCPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |