Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 9/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | ABL2 | P42684 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699497 | 0.89 | IGF1R (0.43) | IGF1RSRCLCKTEKABL1 | |
| SCHEMBL8991337 | 0.85 | ADORA2A (0.41) | IGF1RSRCEGFRADORA2A | |
| SCHEMBL8991292 | 0.84 | ADORA2A (0.51) | SRCLCKTEKABL1EGFR | |
| SCHEMBL7703236 | 0.82 | ADK (0.38) | SRCLCKTEKABL1EGFR | |
| SCHEMBL7699500 | 0.79 | IGF1R (0.42) | IGF1RSRCLCKTEKABL1 | |
| SCHEMBL8991281 | 0.79 | ENPP1 (0.39) | SRCLCKTEKRET | |
| SCHEMBL7696326 | 0.78 | LRRK2 (0.44) | IGF1RSRCLCKTEKABL1 | |
| SCHEMBL8990961 | 0.77 | KDM4E (0.44) | IGF1RSRCLCKTEKABL1 | |
| SCHEMBL8991101 | 0.74 | RIPK2 (0.42) | SRCABL1EGFRABL2CDK1 | |
| SCHEMBL8991365 | 0.74 | ADORA2A (0.41) | IGF1RSRCEGFRADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |