Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811054 | 0.92 | GRM2 (0.44) | POLBGRM2F10 | |
| SCHEMBL7829917 | 0.90 | MAOA (0.47) | POLBGRM2ABCB1CTSVCTSL | |
| SCHEMBL8991499 | 0.85 | POLB (0.47) | POLBGRM2ABCB1 | |
| SCHEMBL8991536 | 0.85 | MAOA (0.49) | POLBABCB1CTSVCTSLF10 | |
| SCHEMBL2837784 | 0.84 | GRM2 (0.47) | GRM2F10 | |
| SCHEMBL8991532 | 0.81 | ABCB1 (0.44) | POLBABCB1CTSVCTSL | |
| SCHEMBL27443061 | 0.78 | POLB (0.45) | POLBABCB1CTSVCTSL | |
| SCHEMBL9611100 | 0.76 | GRM2 (0.49) | GRM2 | |
| SCHEMBL3205152 | 0.75 | GRM2 (0.48) | GRM2F10 | |
| SCHEMBL3049503 | 0.75 | MAPT (0.59) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5529998-A | ANTIBACTERIAL MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0697412-A1 | Benzoxazolyl- and benzo-thiazolyl-oxazolidinones | BAYER AG (DE) | 1996-02-21 | — | — | EP | disclosed |