Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695720 | 0.89 | DYRK1A (0.56) | LRRK2DYRK1AKDM4EALDH1A1LMNA | |
| SCHEMBL8991348 | 0.87 | ALDH1A1 (0.44) | LRRK2DYRK1AKDM4EALDH1A1LMNA | |
| SCHEMBL8991109 | 0.83 | KDM4E (0.59) | LRRK2DYRK1AKDM4EALDH1A1MAPK1 | |
| SCHEMBL8990998 | 0.81 | LRRK2 (0.56) | LRRK2DYRK1AKDM4EALDH1A1MAPK1 | |
| SCHEMBL8991072 | 0.79 | LRRK2 (0.51) | LRRK2DYRK1AKDM4EALDH1A1MAPK1 | |
| SCHEMBL8991123 | 0.78 | KDM4E (0.44) | KDM4EMAPK1HSD17B10TSHRHTT | |
| SCHEMBL8991480 | 0.78 | KDM4E (0.44) | KDM4EMAPK1HSD17B10TSHRHTT | |
| SCHEMBL7700997 | 0.78 | LRRK2 (0.55) | LRRK2DYRK1AKDM4EALDH1A1MAPK1 | |
| SCHEMBL7695719 | 0.77 | LRRK2 (0.53) | LRRK2DYRK1AKDM4EALDH1A1MAPK1 | |
| SCHEMBL7696350 | 0.77 | LRRK2 (0.53) | LRRK2DYRK1AKDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |