Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991442 | 0.87 | LRRK2 (0.53) | ALDH1A1KDM4ELMNALRRK2KMT2A | |
| SCHEMBL8991158 | 0.85 | KMT2A (0.49) | ALDH1A1KDM4ELMNALRRK2PDE4A | |
| SCHEMBL8990982 | 0.82 | GAA (0.42) | ALDH1A1KDM4ELMNALRRK2KMT2A | |
| SCHEMBL8991276 | 0.81 | MEN1 (0.40) | ALDH1A1KDM4ELMNALRRK2KMT2A | |
| SCHEMBL8991122 | 0.79 | PDE4A (0.41) | ALDH1A1KDM4ELMNAPDE4APDE4B | |
| SCHEMBL8991296 | 0.79 | PDE4A (0.41) | ALDH1A1KDM4ELMNAPDE4APDE4B | |
| SCHEMBL7695720 | 0.77 | DYRK1A (0.56) | ALDH1A1KDM4ELMNALRRK2HSD17B10 | |
| SCHEMBL8991067 | 0.77 | KDM4E (0.39) | ALDH1A1KDM4ELMNALRRK2KMT2A | |
| SCHEMBL8991316 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNALRRK2KMT2A | |
| SCHEMBL8991300 | 0.77 | PDE4A (0.43) | ALDH1A1KDM4ELMNAPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |