SCHEMBL8991750

SCHEMBL8991750

CONCC(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FDPS P14324 9/20 0.41
ANPEP P15144 4/20 0.37
MMP1 P03956 4/20 0.35
MMP8 P22894 3/20 0.35
MMP2 P08253 3/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
LAP3 P28838 1/20 0.31
ERAP2 Q6P179 1/20 0.31
MMP3 P08254 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11056866 0.72 ANPEP (0.58) FDPSANPEP
SCHEMBL11699720 0.70 FDPS (0.39) FDPSANPEPMMP1MMP8MMP2
SCHEMBL8764339 0.69 FDPS (0.44) FDPSANPEPMMP2
SCHEMBL8675610 0.68 FDPS (0.48) FDPSANPEPMMP1MMP8MMP2
SCHEMBL8675602 0.68 FDPS (0.42) FDPSANPEPMMP1MMP8MMP2
Phosphoric Acid SCHEMBL17746584 0.67 MMP1 (0.39) MMP1MMP8MMP2CA12CA1
SCHEMBL11367504 0.67 FDPS (0.46) FDPSMMP1MMP8MMP2CA12
SCHEMBL3629699 0.67 FDPS (0.41) FDPSANPEPMMP8MMP2CA12
SCHEMBL8677583 0.67 FDPS (0.41) FDPSANPEP
SCHEMBL17359390 0.67 TSHR (0.42) FDPSMMP1MMP8MMP2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722268-A1 HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS ZENECA LIMITED (GB) 1996-07-24 EP disclosed
WO-1995010188-A2 HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS ZENECA LIMITED (GB) 1995-04-20 WO disclosed