Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | HTR2C | P28335 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916867 | 0.95 | DRD2 (0.61) | DRD2HTR2CHTR1AHTR2AHRH1 | |
| SCHEMBL8917156 | 0.88 | DRD2 (0.58) | DRD2HTR2CHTR1AHTR2AHRH1 | |
| SCHEMBL8919173 | 0.85 | ACHE (0.58) | DRD2HTR2CHTR1AHTR2AHRH1 | |
| SCHEMBL8916604 | 0.83 | HTR6 (0.64) | DRD2HTR2CHTR1AHTR2AHRH1 | |
| SCHEMBL8917276 | 0.83 | HTR2C (0.58) | DRD2HTR2CHTR1AHTR2AHRH1 | |
| SCHEMBL8917771 | 0.83 | DRD2 (0.58) | DRD2HTR2CHTR1AHTR2AHRH1 | |
| SCHEMBL8991886 | 0.82 | DRD2 (0.56) | DRD2HTR2CHTR1AHTR2AHRH1 | |
| Oxalic Acid SCHEMBL8917312 | 0.81 | DRD2 (0.53) | DRD2HTR2CHTR1AHTR2AHRH1 | |
| SCHEMBL8917216 | 0.80 | DRD2 (0.57) | DRD2HTR2CHTR1AHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL8991890 | 0.80 | MCHR1 (0.56) | DRD2HTR2CHTR1AHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | claimed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |