Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899207 | 0.79 | FERMT2 (0.54) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL15912060 | 0.76 | HTR1A (0.58) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL16585552 | 0.75 | HTR1A (0.61) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6223282 | 0.73 | HTR1A (0.73) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL20856477 | 0.72 | HTR1A (0.54) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL28220042 | 0.72 | HTR1A (0.47) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL30307409 | 0.71 | GALR3 (0.59) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7504534 | 0.71 | HTR1A (0.51) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL30307423 | 0.70 | HTR1A (0.54) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL4142709 | 0.70 | HTR1A (0.80) | FERMT2HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621903-A1 | N-HETEROARYL COMPOUNDS | Intervet International B.V. (NL) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041873-A1 | N-HETEROARYL COMPOUNDS | INTERVET INTERNATIONAL B.V. (NL) | 2012-04-05 | — | — | WO | disclosed |