Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836584 | 0.79 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8509845 | 0.79 | MEN1 (0.42) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8992195 | 0.78 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8722327 | 0.75 | MAPKAPK2 (0.41) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10472733 | 0.72 | ALDH1A1 (0.57) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10473961 | 0.71 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10472913 | 0.71 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2174173 | 0.71 | ALDH1A1 (0.67) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15494488 | 0.70 | EGFR (0.61) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8237227 | 0.69 | ALDH1A1 (0.58) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514799-A | 1,1-vinyl substituted nonlinear optical materials | ENICHEM S.P.A. (IT) | 1996-05-07 | — | — | US | disclosed |
| EP-0637774-A1 | 1,1-Vinyl substituted nonlinear optical materials | ENICHEM S.p.A. (IT) | 1995-02-08 | — | — | EP | disclosed |