Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134312 | 0.78 | ALDH1A1 (0.52) | MAPTALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL8992111 | 0.78 | MAPT (0.51) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28836584 | 0.75 | MAPT (0.49) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL611868 | 0.74 | MAPT (0.68) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14982061 | 0.74 | NPC1 (1.00) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14964917 | 0.74 | ALDH1A1 (0.80) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14964918 | 0.74 | ALDH1A1 (0.80) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14964781 | 0.73 | ALDH1A1 (0.78) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14965063 | 0.73 | ALDH1A1 (0.78) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14964780 | 0.73 | ALDH1A1 (0.78) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514799-A | 1,1-vinyl substituted nonlinear optical materials | ENICHEM S.P.A. (IT) | 1996-05-07 | — | — | US | disclosed |
| EP-0637774-A1 | 1,1-Vinyl substituted nonlinear optical materials | ENICHEM S.p.A. (IT) | 1995-02-08 | — | — | EP | disclosed |