Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 7/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992302 | 0.80 | PTPN5 (0.41) | PTPN5PTPN1PGK1PGK2CYP2C9 | |
| SCHEMBL11761689 | 0.79 | PTPN1 (0.60) | PTPN1CYP1A2NPC1RAB9A | |
| SCHEMBL8992581 | 0.73 | PGK1 (0.56) | PTPN1PGK1PGK2ESR1ESR2 | |
| SCHEMBL11762641 | 0.72 | PTPN1 (0.52) | PTPN1PGK1PGK2ESR1ESR2 | |
| SCHEMBL839035 | 0.72 | CYP2A6 (0.56) | ESR1ESR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23908217 | 0.70 | PGK1 (0.43) | PTPN5PTPN1PGK1PGK2ESR1 | |
| Phosphoric Acid SCHEMBL30173246 | 0.70 | ESR1 (0.61) | PTPN1ESR1ESR2CYP1A2ALOX5 | |
| SCHEMBL28800559 | 0.69 | PTPN5 (0.41) | PTPN5PTPN1 | |
| SCHEMBL5859053 | 0.69 | PTPN5 (0.46) | PTPN5PTPN1PGK1PGK2ESR1 | |
| Hydrogen Peroxide SCHEMBL8609891 | 0.69 | PTPN1 (0.52) | PTPN5PTPN1PGK1PGK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | claimed |