Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | ACP3 | P15309 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992169 | 0.85 | PTPN5 (0.40) | PTPN5PPARGPPARAACP3HDAC8 | |
| SCHEMBL8992156 | 0.80 | PTPN5 (0.43) | PTPN5PGK1PGK2CYP2C9PTPN1 | |
| SCHEMBL8992172 | 0.74 | PGK1 (0.53) | ACP3IDH1HDAC8HDAC6PGK1 | |
| SCHEMBL30545233 | 0.73 | ENPP3 (0.47) | HDAC8HDAC6MCL1ACMSD | |
| SCHEMBL838870 | 0.73 | ENPP3 (0.47) | HDAC8HDAC6MCL1ACMSD | |
| Phosphine SCHEMBL28240948 | 0.72 | ENPP3 (0.46) | PPARGPPARAHDAC8HDAC6MCL1 | |
| SCHEMBL3346090 | 0.71 | ACP3 (0.61) | ACP3PGK1PGK2PTPRCPTPN1 | |
| SCHEMBL8925299 | 0.71 | PPARG (0.40) | PPARGPPARAHDAC8HDAC6CYP2C9 | |
| SCHEMBL3357709 | 0.70 | ALDH1A1 (0.47) | PPARGPPARAHDAC8HDAC6CYP2C9 | |
| SCHEMBL3390400 | 0.69 | PGK1 (0.52) | PTPN5ACP3PGK1PGK2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | claimed |