Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.60 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11762641 | 0.93 | PTPN1 (0.52) | PTPN1PTPRC | |
| SCHEMBL11759232 | 0.85 | PTPN1 (0.45) | PTPN1PTPRC | |
| SCHEMBL3390400 | 0.80 | PGK1 (0.52) | PTPN1PTPRC | |
| SCHEMBL7870277 | 0.80 | PGK1 (0.44) | PTPN1 | |
| SCHEMBL11760531 | 0.79 | PTPN1 (0.49) | PTPN1PTPRC | |
| SCHEMBL8992156 | 0.79 | PTPN5 (0.43) | PTPN1CYP1A2RAB9ANPC1 | |
| SCHEMBL1556937 | 0.78 | PTPN1 (0.52) | PTPN1HDAC1 | |
| Hydrogen Peroxide SCHEMBL8609891 | 0.78 | PTPN1 (0.52) | PTPN1HDAC1 | |
| SCHEMBL9398056 | 0.77 | PTPN1 (0.66) | PTPN1PTPRCRAB9ANPC1 | |
| SCHEMBL11759783 | 0.77 | PTPN1 (0.46) | PTPN1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061681-A | Method for the preparation of mono- or poly [dialkyl or dicycloalkylphosphonylmethyl] aromatic carbocyclic compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |