Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827129 | 0.80 | ATM (0.34) | TSHRATMALDH1A1KCNN4CYP2C19 | |
| SCHEMBL6311548 | 0.72 | ALDH1A1 (0.38) | TSHRALDH1A1KCNN4CYP2C19HIF1A | |
| SCHEMBL1148767 | 0.72 | KCNN4 (0.40) | TSHRATMALDH1A1KCNN4CYP2C19 | |
| SCHEMBL27880149 | 0.72 | ALDH1A1 (0.38) | TSHRALDH1A1KCNN4CYP2C19HIF1A | |
| SCHEMBL342226 | 0.72 | ALDH1A1 (0.38) | TSHRALDH1A1KCNN4CYP2C19HIF1A | |
| SCHEMBL28457377 | 0.70 | KCNN4 (0.46) | TSHRATMALDH1A1KCNN4CYP2C19 | |
| SCHEMBL8650476 | 0.69 | TSHR (0.36) | TSHRALDH1A1KCNN4CYP2C19HIF1A | |
| SCHEMBL28194983 | 0.69 | GAA (0.38) | TSHRALDH1A1CYP2C19HIF1A | |
| SCHEMBL7816528 | 0.69 | MAPT (0.35) | TSHRATMALDH1A1HTTMAOA | |
| SCHEMBL3193710 | 0.68 | CYP2C19 (0.50) | TSHRATMALDH1A1KCNN4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5256824-A | Anticholinergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |