SCHEMBL8992377

SCHEMBL8992377

Cc1c(C2=CC(=O)C(=O)c3ccccc32)[nH]c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 7/20 0.62
PTPN1 P18031 10/20 0.56
PTPRF P10586 2/20 0.56
CDC25B P30305 2/20 0.56
HKDC1 Q2TB90 2/20 0.44
CCR6 P51684 1/20 0.44
DAO P14920 1/20 0.44
DDO Q99489 1/20 0.44
NSD2 O96028 1/20 0.43
OPRM1 P35372 1/20 0.43
OPRD1 P41143 1/20 0.43
AHR P35869 1/20 0.43
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9571998 0.88 PTPRC (0.51) PTPRCPTPN1PTPRFCDC25BHKDC1
SCHEMBL8992318 0.82 PTPRC (0.70) PTPRCPTPN1PTPRFCDC25BHKDC1
SCHEMBL6232476 0.77 PTPRC (1.00) PTPRCPTPN1PTPRFCDC25BHKDC1
SCHEMBL1784241 0.76 PTPRC (0.46) PTPRCPTPN1PTPRFCDC25BHKDC1
SCHEMBL9562286 0.73 CCR6 (0.62) PTPRCPTPN1PTPRFCDC25BHKDC1
SCHEMBL8992461 0.72 PTPN1 (1.00) PTPRCPTPN1PTPRFCDC25BHKDC1
SCHEMBL8600693 0.72 PTPN1 (0.75) PTPRCPTPN1PTPRFCDC25BHKDC1
SCHEMBL7195762 0.72 AHR (0.70) DAODDOAHRCYP1A2CYP2C19
Anthraquinone SCHEMBL1900459 0.68 ALDH1A1 (0.67) PTPRCCDC25BAHRCYP1A2TNKS2
SCHEMBL27807142 0.68 DAO (0.62) DAODDOAHRCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0560682-B1 Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones OREAL (FR) 1996-08-07 EP claimed
EP-0560682-A1 Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones L'OREAL (FR) 1993-09-15 EP claimed
EP-0560682-B1 Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones OREAL (FR) 1996-08-07 EP disclosed
EP-0560682-A1 Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones L'OREAL (FR) 1993-09-15 EP disclosed