Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 1.00 |
| ▸ | PTPRC | P08575 | 7/20 | 1.00 |
| ▸ | PTPRF | P10586 | 2/20 | 1.00 |
| ▸ | CDC25B | P30305 | 2/20 | 1.00 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.54 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | PRKCB | P05771 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | PRKACG | P22612 | 1/20 | 0.54 |
| ▸ | PRKACB | P22694 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572016 | 0.87 | PTPN1 (0.77) | PTPN1PTPRCPTPRFCDC25BSIRT2 | |
| SCHEMBL7951074 | 0.84 | PTPN1 (0.73) | PTPN1PTPRCPTPRFCDC25BSIRT2 | |
| SCHEMBL27898411 | 0.78 | PTPN1 (0.64) | PTPN1PTPRCPTPRFCDC25BSIRT2 | |
| SCHEMBL27771326 | 0.76 | PTPN1 (0.61) | PTPN1PTPRCPTPRFCDC25BSIRT2 | |
| SCHEMBL27795880 | 0.76 | PTPN1 (0.61) | PTPN1PTPRCPTPRFCDC25BSIRT2 | |
| SCHEMBL1158441 | 0.75 | PTPRC (0.60) | PTPN1PTPRCPTPRFCDC25BSIRT2 | |
| SCHEMBL9572019 | 0.75 | PTPN1 (0.59) | PTPN1PTPRCPTPRFCDC25BSIRT2 | |
| SCHEMBL8600693 | 0.74 | PTPN1 (0.75) | PTPN1PTPRCPTPRFCDC25BNSD2 | |
| SCHEMBL5879323 | 0.73 | PTPRC (0.58) | PTPN1PTPRCPTPRFCDC25BSIRT2 | |
| SCHEMBL6235934 | 0.73 | PTPN1 (1.00) | PTPN1PTPRCPTPRFCDC25BNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | claimed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | disclosed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |