Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 7/20 | 0.70 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.62 |
| ▸ | CCR6 | P51684 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.56 |
| ▸ | PTPRF | P10586 | 2/20 | 0.56 |
| ▸ | CDC25B | P30305 | 2/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562286 | 0.88 | CCR6 (0.62) | PTPRCHKDC1CCR6PTPN1PTPRF | |
| SCHEMBL6232476 | 0.82 | PTPRC (1.00) | PTPRCHKDC1CCR6PTPN1PTPRF | |
| SCHEMBL8992377 | 0.82 | PTPRC (0.62) | PTPRCHKDC1CCR6PTPN1PTPRF | |
| SCHEMBL9561901 | 0.81 | CCR6 (0.56) | PTPRCHKDC1CCR6IMPDH2CYP1A2 | |
| SCHEMBL9572012 | 0.78 | BACE1 (0.57) | PTPRCHKDC1CCR6CDC25BNSD2 | |
| SCHEMBL9562546 | 0.78 | BACE1 (0.57) | PTPRCHKDC1CCR6CDC25BNSD2 | |
| SCHEMBL7716546 | 0.77 | CCR6 (0.53) | PTPRCHKDC1CCR6CDC25BNSD2 | |
| SCHEMBL29094069 | 0.77 | CCR6 (1.00) | PTPRCHKDC1CCR6IMPDH2CYP1A2 | |
| SCHEMBL9561883 | 0.76 | HKDC1 (0.52) | PTPRCHKDC1CCR6PTPN1PTPRF | |
| SCHEMBL9561922 | 0.76 | CCR6 (0.51) | PTPRCHKDC1CCR6IMPDH2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | claimed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | disclosed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |