Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.58 |
| ▸ | PTPRF | P10586 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | CDC25B | P30305 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.57 |
| ▸ | PRKCB | P05771 | 3/20 | 0.57 |
| ▸ | PRKCA | P17252 | 2/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.57 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.57 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | PRKCG | P05129 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | PRKACG | P22612 | 1/20 | 0.57 |
| ▸ | PRKACB | P22694 | 1/20 | 0.57 |
| ▸ | CCND1 | P24385 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951074 | 0.80 | PTPN1 (0.73) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL8314810 | 0.80 | TDO2 (0.49) | CCNE2CDK4PRKACAPRKACGPRKACB | |
| SCHEMBL7197287 | 0.77 | PRKCB (0.68) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL29771997 | 0.75 | PRKCB (0.65) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL1158441 | 0.75 | PTPRC (0.60) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL2193383 | 0.75 | PRKCB (0.65) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL1202543 | 0.74 | IMPDH2 (0.63) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL8992461 | 0.73 | PTPN1 (1.00) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL6824529 | 0.73 | PTPRC (0.55) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL9572016 | 0.73 | PTPN1 (0.77) | PTPRCPTPRFPTPN1CDC25BSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978298-A | Bis-indole maleimide fluorescence sensor containing aromatic amide group | 广东石油化工学院 | 2020-11-24 | — | — | CN | claimed |
| CN-111978298-A | Bis-indole maleimide fluorescence sensor containing aromatic amide group | 广东石油化工学院 | 2020-11-24 | — | — | CN | disclosed |
| CN-101812097-A | Indole carbazole and bisindole maleimide alkaloid and its production and application | OCEAN UNIV CHINA | 2010-08-25 | — | — | CN | disclosed |
| US-7151108-B2 | Anticarcinogenic, antiproliferative, and antitumor agents | LES LABORATORIES SERVIER (FR) | 2006-12-19 | — | — | US | disclosed |
| EP-1411057-B1 | [3,4-a:3,4-c]carbazole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-04-27 | — | — | EP | disclosed |
| US-20040077672-A1 | Anticarcinogenic, antiproliferative, and antitumor agents | LES LABORATOIRES SERVIER (FR) | 2004-04-22 | — | — | US | disclosed |
| EP-1411057-A1 | [3,4-a:3,4-c]carbazole derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2004-04-21 | — | — | EP | disclosed |
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | disclosed |
| US-5547976-A | VIRICIDES, HERPES VIRUS, CYTOMEGALOVIRUS; CARDIOVASCULAR DISORDERS | BURROUGHS WELLCOME CO. (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0630241-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018765-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077672-A1 | Anticarcinogenic, antiproliferative, and antitumor agents | XDH, TOP2A, TOP1 | PTPRC 2403/4885PTPRF 1942/4885PTPN1 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.