Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CASR | P41180 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992651 | 0.92 | RAB9A (0.47) | RAB9AMAPTCASRALDH1A1HPGD | |
| SCHEMBL8129548 | 0.90 | RAB9A (0.45) | RAB9AMAPTCASRALDH1A1HPGD | |
| SCHEMBL8992691 | 0.84 | NPY5R (0.51) | RAB9AMAPTALDH1A1HTTKMT2A | |
| SCHEMBL8903055 | 0.83 | RAB9A (0.42) | RAB9AMAPTCASRALDH1A1HPGD | |
| SCHEMBL8663889 | 0.82 | ACE (0.49) | MAPK1 | |
| SCHEMBL7425443 | 0.81 | RAB9A (0.71) | RAB9AMAPTALDH1A1HPGDHTT | |
| SCHEMBL8992625 | 0.77 | ALDH1A1 (0.48) | RAB9AMAPTALDH1A1HPGDKMT2A | |
| SCHEMBL12993342 | 0.74 | RAB9A (0.60) | RAB9AMAPTALDH1A1HPGDHTT | |
| SCHEMBL12993060 | 0.74 | RAB9A (0.60) | RAB9AMAPTALDH1A1HTTKMT2A | |
| SCHEMBL8472195 | 0.73 | NPY5R (0.59) | RAB9AMAPTALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719251-A1 | BICYCLO (2.2.2) OCTANE DERIVATIVES CHOLECYSTOKININ AND/OR GASTRIN ANTAGONISTS | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995005359-A1 | BICYCLO (2.2.2) OCTANE DERIVATIVES CHOLECYSTOKININ AND/OR GASTRIN ANTAGONISTS | JAMES BLACK FOUNDATION LIMITED (GB) | 1995-02-23 | — | — | WO | disclosed |