Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992639 | 0.88 | GABRA1 (0.44) | GAAALDH1A1PPARGPPARDKDM4E | |
| SCHEMBL9556597 | 0.85 | GRM2 (0.39) | GRM2CYP11B1CYP11B2CYP2C9 | |
| SCHEMBL4948816 | 0.79 | ALDH1A1 (0.42) | GAAALDH1A1PPARGPPARDKDM4E | |
| SCHEMBL9259062 | 0.78 | GABRA1 (0.45) | GAAALDH1A1PPARGPPARDKDM4E | |
| SCHEMBL9326924 | 0.76 | SMN1; SMN2 (0.57) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9327112 | 0.76 | CYP11B1 (0.46) | GAAKDM4EGRM2CYP11B1CYP11B2 | |
| SCHEMBL8054086 | 0.75 | CYP11B1 (0.31) | GAAALDH1A1PPARGPPARDKDM4E | |
| SCHEMBL8054082 | 0.75 | CYP11B1 (0.31) | GAAALDH1A1PPARGPPARDKDM4E | |
| SCHEMBL9325558 | 0.74 | SMN1; SMN2 (0.55) | GAAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL10752849 | 0.74 | CYP11B1 (0.56) | GAAALDH1A1PPARGPPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433826-B1 | Fluorophenylpyridines | HOECHST AG (DE) | 1996-07-10 | — | — | EP | disclosed |