SCHEMBL4948816

SCHEMBL4948816

C=CCc1ccc(-c2ccc(CC=C)cn2)nc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
SMN1; SMN2 Q16637 6/20 0.42
CYP3A4 P08684 3/20 0.42
TP53 P04637 2/20 0.42
XDH P47989 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
MAPT P10636 5/20 0.41
KDM4E B2RXH2 3/20 0.41
PPARG P37231 2/20 0.41
PPARD Q03181 2/20 0.41
MEN1 O00255 2/20 0.41
GAA P10253 2/20 0.41
HPGD P15428 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH2 P05091 1/20 0.41
GABRA1 P14867 1/20 0.41
AKR1B1 P15121 1/20 0.41
CNR1 P21554 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23063604 0.84 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2CYP3A4TP53XDH
SCHEMBL9326066 0.82 RAB9A (0.60) ALDH1A1SMN1; SMN2TP53MAPTKDM4E
SCHEMBL8649755 0.82 RAB9A (0.57) ALDH1A1SMN1; SMN2TP53XDHMAPT
SCHEMBL10615812 0.80 RAB9A (0.56) ALDH1A1SMN1; SMN2TP53XDHMAPT
SCHEMBL11124858 0.80 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2CYP3A4TP53XDH
SCHEMBL8992683 0.79 GAA (0.41) ALDH1A1SMN1; SMN2TP53XDHMAPT
SCHEMBL3804734 0.78 CYP11B1 (0.42) ALDH1A1SMN1; SMN2CYP3A4TP53XDH
SCHEMBL8585824 0.78 GABRA1 (0.48) ALDH1A1SMN1; SMN2CYP3A4TP53XDH
SCHEMBL646817 0.78 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2CYP3A4TP53XDH
SCHEMBL12697280 0.78 GAA (0.46) ALDH1A1MAPTKDM4EGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470762-B2 Living radical polymerization of acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA (US) 2008-12-30 US claimed
US-7345127-B2 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA (US) 2008-03-18 US claimed
US-20080039601-A1 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA 2008-02-14 US claimed
EP-1853638-A1 LIVING RADICAL POLYMERIZATION OF HALOGEN-CONTAINING AND ACRYLIC MONOMERS AND THE FORMATION OF BLOCK COPOLYMERS THEREFROM The University of Pennsylvania (US) 2007-11-14 EP claimed
WO-2006080928-A1 LIVING RADICAL POLYMERIZATION OF HALOGEN-CONTAINING AND ACRYLIC MONOMERS AND THE FORMATION OF BLOCK COPOLYMERS THEREFROM UNIVERSITY OF PENNSYLVANIA (US) 2006-08-03 WO claimed
US-20050131186-A1 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom PENNSYLVANIA, UNIVERSITY OF 2005-06-16 US claimed
US-7470762-B2 Living radical polymerization of acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA (US) 2008-12-30 US disclosed
US-7345127-B2 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA (US) 2008-03-18 US disclosed
US-20080039601-A1 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA 2008-02-14 US disclosed
EP-1853638-A1 LIVING RADICAL POLYMERIZATION OF HALOGEN-CONTAINING AND ACRYLIC MONOMERS AND THE FORMATION OF BLOCK COPOLYMERS THEREFROM The University of Pennsylvania (US) 2007-11-14 EP disclosed
WO-2006080928-A1 LIVING RADICAL POLYMERIZATION OF HALOGEN-CONTAINING AND ACRYLIC MONOMERS AND THE FORMATION OF BLOCK COPOLYMERS THEREFROM UNIVERSITY OF PENNSYLVANIA (US) 2006-08-03 WO disclosed
US-20050131186-A1 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom PENNSYLVANIA, UNIVERSITY OF 2005-06-16 US disclosed